PROJECT: JTC2022 - Networking Chronic Pain: PAC-MAN

Pain After Covid-Multidisciplinary Action Network

Abstract

Over 200 million patients (pts) worldwide have fatigue, widespread muscle pain, joint and chest pain due to COVID-19 infection. Little is known on onset, pathophysiology and clinical history of chronic pain post-COVID, leaving doctors at loss when it comes to specifically identify and diagnose pts and prescribe most effective treatments. To advance knowledge on post-COVID chronic pain, to discuss current clinical gaps, develop potential solutions for these pressing issues we propose a multidisciplinary consortium: -clinicians working with long COVID pts and specific knowledge of chronic post-COVID pain syndrome. -clinical experts in chronic pain syndromes in specific settings: pediatric and chronic postoperative pain, chronic pain neuromodulation; -basic scientists applying genomics for a better understanding of pain pathophysiology and using glycomics to predict long COVID and stratify the risk of pts to develop long COVID-associated severe illness; -translational scientists, pharmacology and nanomedicine experts for development of new nanotherapies to tackle chronic pain, inflammation and immune activation; -startups, established biotech companies interested in development of new therapeutic tools for pain, incl.an international CDMO involved in industrialization of pharmaceutical/nutraceutical products, scientific associations (Redirect) for spreading the culture of rational approach to chronic postoperative pain and inflammatory chronic pain.

Keywords

chronic pain, Long COVID, Multidisciplinary approach, Translation to the clinic

Call topic

Networking Chronic Pain

Proposed runtime

2023 - 2024

Project team

Ennio Tasciotti (Coordinator)
Italy
Cesar Fernandez-de-las-Penas
Spain
Andrea Fanelli
Italy
Sam Eldabe
United Kingdom (MRC)
Lars Arendt-Nielsen
Denmark
Jean-Pierre Van Buyten
Belgium
Massimo Allegri
Switzerland
Carolina Muscoli
Italy
Pablo Ingelmo
Canada
Assaf Zinger
Israel
Dragan Primorac
Croatia
Filippo Sertorio
Italy
Nicoletta Marchesi
Italy
Gordan Lauc
Croatia
Gisele Pickering
France
Marina Lusic
Germany
Thomas Volk
Germany
Luda Diatchenko
Canada

Lay summary