ENTRUST-PE: Enhancing Trust in Pain Evidence
Abstract
Patients with chronic pain, clinicians and the public are often poorly served by an evidence architecture that contains multiple structural weaknesses which reduce confidence in treatment practice. Weaknesses include incomplete research governance, inadequate stakeholder engagement, poor methodological rigour and incomplete reporting, a lack of data accessibility/ transparency, and a failure to communicate findings with appropriate balance (without spin) and research misconduct. These issues span pre-clinical research, clinical trials, systematic reviews and impact on the development of clinical guidance and practic update. Combined, these weaknesses serve to increase uncertainty in this area of study and practice, drive the provision of low value care, increase costs and impede the discovery of more effective solutions.
The central objective of our proposed network is to develop ENTRUST-PE, a novel integrated framework for enhancing and facilitating the trustworthiness of evidence for chronic pain. This will involve identifying and synthesising a range of available resources into a common framework that supports researchers, editors and publishers to minimise threats to the trustworthiness of pain research. The ENTRUST-PE framework will provide support for researchers, reviewers and editors to optimise the trustworthiness of new research and help consumers/ users of research to evaluate the quality and trustworthiness of existing evidence in chronic pain
Keywords
open science, Chronic pain, evidence, trustworthiness
Call topic
Networking Chronic Pain
Proposed runtime
2023 - 2024
Project team
O'Connell Neil (Coordinator)
UK
Neil O'Connell
United Kingdom
Christopher Eccleston
UK
Emma Fisher
UK
Andrew Rice
United Kingdom
Nadia Soliman
UK
Vollert Jan
UK
Esther Pogatzki-Zahn
Germany (BMBF)
Gisele Pickering
France
Roger Knaggs
UK
Geert Crombez
Belgium
Georgia Richards
UK
Jack Wilkinson
UK
Dennis Turk
USA
Amanda Williams
UK
Thomas R. Toelle
Germany
Francis Keefe
USA
Tonya Palermo
USA
Elaine Wainwright
UK
Stewart Gavin
United Kingdom